Tel:
China Supplement Raw Materials manufacturer
Nanjing Health Herb Bio-Tech Co., Ltd

Health care products, food additives, cosmetics additives, plastic additives

Home ProductsPharmaceutical Raw Materials

Neostigmine methyl sulfate 51-60-5 anticholinesterase agent cholinesterase inhibitor

Neostigmine methyl sulfate 51-60-5 anticholinesterase agent cholinesterase inhibitor

Neostigmine methyl sulfate 51-60-5 anticholinesterase agent cholinesterase inhibitor

Product Details:

Place of Origin: CHINA
Brand Name: Health Herb
Model Number: USP

Payment & Shipping Terms:

Minimum Order Quantity: 1KGS
Price: Negotiable
Packaging Details: 1kg/bag, 25kgs/drum
Delivery Time: 7 DAYS
Supply Ability: 2MT/MONTH
Contact Now
Detailed Product Description
Name: Neostigmine Methyl Sulfate CAS: 51-60-5
Standard: USP Color: White Crystalline Powder
Other Name: Neostigmine Methylsulfate Function: Anticholinesterase Agent

We supply good quality Neostigmine methyl sulfate 51-60-5

 

Introduction

 

Neostigmine Methylsulfate, an anticholinesterase agent, is a bitter tasting, white crystalline powder and is very soluble in water and soluble in alcohol. Neostigmine Methylsulfate, USP is a sterile, nonpyrogenic solution intended for intramuscular, subcutaneous or slow intravenous use.

 

A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.

 

Application

 

Neostigmine is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor. The drug inhibits acetylcholinesterase which is responsible for the degredation of acetylcholine. So, with acetylcholinesterase inhibited, more acetylcholine is present By interfering with the breakdown of acetylcholine, neostigmine indirectly stimulates both nicotinic and muscarinic receptors which are involved in muscle contraction.. It does not cross the blood-brain barrier.

 

Neostigmine Methylsulfate, USP is indicated for:

- the symptomatic control of myasthenia gravis when oral therapy is impractical.
- the prevention and treatment of postoperative distention and urinary retention after mechanical obstruction has been excluded.
- reversal of effects of non-depolarizing neuromuscular blocking agents (e.g., tubocurarine, metocurine, gallamine or pancuronium) after surgery.

 

Basic information

 

  •  Appearance: Crystalline Solid
  •  Molecular Weight: 334.43
  •  Boiling Point: 457
  •  Melting Point: 175-177 °C(lit.)
  •  Flash Point: 224
  •  Storage Temperature: −20°C
  •  Solubility: 1g/10mL in water
  •  Stability: Stable at normal temperatures and pressures.

 

COA

 

Items

Specifications

Results

Identification

Meet with the requirements

Conforms

Appearance

White crystalline powder

Conforms

Melting Point

143℃ ~ 149℃

143.1~145.8℃

Loss on drying

≤1.0%

0.56%

Residue on ignition

≤0.1%

0.07%

Chloride

Meet with the requirements

Not detected

Sulfate ion

Meet with the requirements

Not detected

Assay

98.0% ~102.0%

99.33%

Conclusion: It complies with USP35

 

Neostigmine methyl sulfate 51-60-5 anticholinesterase agent cholinesterase inhibitor

Contact Details
Nanjing Health Herb Bio-Tech Co., Ltd

Contact Person: Pan Lin

Tel: 86-25-83310216

Send your inquiry directly to us (0 / 3000)

Nanjing Health Herb Bio-Tech Co., Ltd
Room1103, 5 Building, No.118, NanTong Street, Nanjing China
Tel:86-25-83310216-86638485
Privacy Policy China Good Quality Supplier. Copyright © 2018 - 2019 supplementrawmaterials.com. All Rights Reserved.