Health care products, food additives, cosmetics additives, plastic additives
Place of Origin: | CHINA |
Brand Name: | Health Herb |
Model Number: | USP |
Minimum Order Quantity: | 1KGS |
---|---|
Price: | Negotiable |
Packaging Details: | 1kg/bag, 10kgs/drum |
Delivery Time: | 7 DAYS |
Supply Ability: | 2MT/MONTH |
Name: | Dexamethasone Sodium Phosphate | CAS: | 2392-39-4 |
---|---|---|---|
MF: | C22H28FNa2O8P | MW: | 516.4 |
Standard: | USP | Color: | White Powder |
Package: | 1kg/bag, 10kgs/drum | Function: | Anti-inflammatory |
High Light: | pharma raw material,pharmaceutical grade raw materials |
We supply good quality Dexamethasone sodium phosphate CAS 2392-39-4
Introduction
Dexamethasone Sodium Phosphate is a systemic corticosteroid. Dexamethasone Sodium Phosphate induces apoptosis and inhibits sodium phosphate symporter. Dexamethasone Sodium Phosphate is also used in the treatment of emetic effects of cancer therapy and epicondylitis. Dexamethasone Sodium Phosphate is an activator of GR.
Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant.Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than prednisone, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary - adrenal strong inhibition.
Function
Dexamethasone sodium phosphate is a synthetic adrenocortical steroid used to treat inflammatory and autoimmune conditions;
Application
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation,
thereby reducing inflammation performance. Hormone suppression of inflammatory cells,including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis,
lysosomal enzyme release and synthesis and release of inflammatory chemical mediators.Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response.Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
Basic information
Product Name | Dexamethasone sodium phosphatec |
Other Name | Decadronphosphate |
Specification | 99% |
Appearance | White or almost white crystalline powder |
CAS NO. | 2392-39-4 |
Molecular Formula | C22H28FNa2O8P |
Molecular Weight | 516.4 |
Grade | Medicine Grade |
Test method | HPLC |
COA
Items |
Specifications |
Results |
Character |
White or almost white, very hygroscopic powder |
Almost white, very hygroscopic powder |
Appearance of solution |
Clear, not more intensely coloured than reference solution B7 |
Conforms |
Inorganic phosphates |
≤1.0% |
<1% |
Identification |
(1) Complies by IR |
Conforms |
(2) Complies by TLC |
Conforms |
|
Solubility |
Freely soluble in water, slightly soluble in 96% ethanol, practically insoluble in methylene chloride. |
Conforms |
Sepecific optical rotation |
+75°~+83.0° |
+76.0° |
Ethanol and water |
Not more than 13.0% |
10.7% |
pH |
7.5~9.5 |
8.32 |
Related substance |
A ≤0.5% |
Not detected |
B ≤0.5% |
0.06% |
|
Total impurity ≤1.0% |
0.57% |
|
Residual solvents |
Methanol≤3000ppm |
1397ppm |
Ethanol≤5000ppm |
110ppm |
|
Acetone≤5000ppm |
1103ppm |
|
THF≤720ppm |
Not detected |
|
Benzene≤2ppm |
Not detected |
|
Ethyl acetate≤5000ppm |
16ppm |
|
Assay (dried basis) | Contains 97.0% to 103.0% of C22H28FNa2O8P, calculated with anhydrous ethanol-free | 99.5% |
Conclusion: Conclusion: It complies with EP7 |
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