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Dexamethasone sodium phosphate CAS 2392-39-4 DSP DEXAMETHASONE 21 PHOSPHATE SODIUM

Dexamethasone sodium phosphate CAS 2392-39-4 DSP DEXAMETHASONE 21 PHOSPHATE SODIUM

Dexamethasone sodium phosphate CAS 2392-39-4 DSP DEXAMETHASONE 21 PHOSPHATE SODIUM

Product Details:

Place of Origin: CHINA
Brand Name: Health Herb
Model Number: USP

Payment & Shipping Terms:

Minimum Order Quantity: 1KGS
Price: Negotiable
Packaging Details: 1kg/bag, 10kgs/drum
Delivery Time: 7 DAYS
Supply Ability: 2MT/MONTH
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Detailed Product Description
Name: Dexamethasone Sodium Phosphate CAS: 2392-39-4
MF: C22H28FNa2O8P MW: 516.4
Standard: USP Color: White Powder
Package: 1kg/bag, 10kgs/drum Function: Anti-inflammatory

We supply good quality Dexamethasone sodium phosphate CAS 2392-39-4

 

Introduction

 

Dexamethasone Sodium Phosphate is a systemic corticosteroid. Dexamethasone Sodium Phosphate induces apoptosis and inhibits sodium phosphate symporter. Dexamethasone Sodium Phosphate is also used in the treatment of emetic effects of cancer therapy and epicondylitis. Dexamethasone Sodium Phosphate is an activator of GR.

 

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant.Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than prednisone, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary - adrenal strong inhibition.

 

Function

 

Dexamethasone sodium phosphate is a synthetic adrenocortical steroid used to treat inflammatory and autoimmune conditions;

  •  Dexamethasone sodium phosphate is used to treat conditions such as skin conditions, ulcerative colitis, psoriasis, arthritis, allergic disorders and breathing related problems;
  •  Dexamethasone sodium phosphate is given to cancer patients undergoing chemotherapy, to prevent certain side-effects:
  •  Dexamethasone sodium phosphate is also used in the treatment of high altitude cerebral edema.

 

Application

 

1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation,

thereby reducing inflammation performance. Hormone suppression of inflammatory cells,including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis,

lysosomal enzyme release and synthesis and release of inflammatory chemical mediators.Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.


2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response.Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.

 

Basic information

 

Product Name Dexamethasone sodium phosphatec
Other Name Decadronphosphate
Specification 99%
Appearance White or almost white crystalline powder
CAS NO. 2392-39-4
Molecular Formula C22H28FNa2O8P
Molecular Weight 516.4
Grade Medicine Grade
Test method HPLC

 

 

COA

 

Items

Specifications

Results

Character

White or almost white, very hygroscopic powder

Almost white, very hygroscopic powder

Appearance of solution

Clear, not more intensely coloured than reference solution B7

Conforms

Inorganic phosphates

≤1.0%

<1%

Identification

(1) Complies by IR

Conforms

(2) Complies by TLC

Conforms

Solubility

Freely soluble in water, slightly soluble in 96% ethanol, practically insoluble in methylene chloride.

Conforms

Sepecific optical rotation

+75°~+83.0°

+76.0°

Ethanol and water

Not more than 13.0%

10.7%

pH

7.5~9.5

8.32

Related substance

A ≤0.5%

Not detected

B ≤0.5%

0.06%

Total impurity ≤1.0%

0.57%

Residual solvents

Methanol≤3000ppm

1397ppm

Ethanol≤5000ppm

110ppm

Acetone≤5000ppm

1103ppm

THF≤720ppm

Not detected

Benzene≤2ppm

Not detected

Ethyl acetate≤5000ppm

16ppm

Assay (dried basis) Contains 97.0% to 103.0% of C22H28FNa2O8P, calculated with anhydrous ethanol-free 99.5%
Conclusion: Conclusion: It complies with EP7
 

Dexamethasone sodium phosphate CAS 2392-39-4 DSP DEXAMETHASONE 21 PHOSPHATE SODIUM

Contact Details
Nanjing Health Herb Bio-Tech Co., Ltd

Contact Person: Pan Lin

Tel: 86-25-83310216

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