Health care products, food additives, cosmetics additives, plastic additives
|Place of Origin:||CHINA|
|Brand Name:||Health Herb|
|Minimum Order Quantity:||5KGS|
|Delivery Time:||7 DAYS|
|EINECS No:||246-551-2||Usage:||Pharmaceutical Grade|
chondroitin sulphate sodium,
chondroitin sulfate sodium salt
We supply pharmaceutical grade Chondroitin Sulphate 9007-28-7
Chondroitin sulfate is a kind of acid mucopolysaccharide extracted from healthy domestic animal cartilage. It is mainly composed of chondroitin sulfate A, C and other types of chondroitin sulfate. It widely exists in animal’s cartilage, hyoid bone and nasal throat, and also in bone tendon, ligament, skin, cornea and other tissues. The main existence of Chondroitin sulfate is sodium chondroitin sulfate.
1. Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).
2. Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.
3. As part of aggrecan, chondroitin sulfate is a major component of cartilage. The tightly packed and highly charged sulfate groups of chondroitin sulfate generate electrostatic repulsion that provides much of the resistance of cartilage to compression. Loss of chondroitin sulfate from the cartilage is a major cause of osteoarthritis.
Chondroitin sulfate was originally isolated well before the structure was characterised, leading to changes in terminology with time. Early researchers identified different fractions of the substance with letters.
|Letter identification||Site of sulfation||Systematic name|
|Chondroitin sulfate A||carbon 4 of the N-acetylgalactosamine (GalNAc) sugar||chondroitin-4-sulfate|
|Chondroitin sulfate C||carbon 6 of the GalNAc sugar||chondroitin-6-sulfate|
|Chondroitin sulfate D||carbon 2 of the glucuronic acid and 6 of the GalNAc sugar||chondroitin-2,6-sulfate|
|Chondroitin sulfate E||carbons 4 and 6 of the GalNAc sugar||chondroitin-4,6-sulfate|
|Appearance||White to off-white powder|
|Identification||Infra Red Confirmed|
|Loss on drying||NMT10%|
|PH (1% H2O Solution)||5.5-7.5|
|Specific Rotation||-20°- - 30°|
|Residue on Ignition||20%-30%|
|Clarity (5% H2O Solution)||NMT0.35@420nm|
|Organic volatile impurities||Meet the requirements|
|Total Bacteria Count||NMT1000Cfu/g|
|Yeast & Molds||NMT100Cfu/g|
Contact Person: Pan Lin